Evaluation of in vitro released Wuchereria bancrofti third stage larval antigens for detection of Bancroftian filariasis.
Identifieur interne : 00DA24 ( Main/Exploration ); précédent : 00DA23; suivant : 00DA25Evaluation of in vitro released Wuchereria bancrofti third stage larval antigens for detection of Bancroftian filariasis.
Auteurs : P A Carvalho [Inde] ; G R Rajasekariah ; L. Desphande ; P B Parab ; U R Rao ; D. SubrahmanyamSource :
- Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) [ 0177-2392 ] ; 1990.
Descripteurs français
- KwdFr :
- MESH :
- analyse : Anticorps antihelminthe.
- diagnostic : Filariose lymphatique, Filarioses.
- immunologie : Antigènes d'helminthe, Sérums immuns, Wuchereria, Wuchereria bancrofti.
- Animaux, Humains, Test ELISA, Valeur prédictive des tests.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Antibodies, Helminth.
- chemical , immunology : Antigens, Helminth, Immune Sera.
- diagnosis : Elephantiasis, Filarial, Filariasis.
- immunology : Wuchereria, Wuchereria bancrofti.
- Animals, Enzyme-Linked Immunosorbent Assay, Humans, Predictive Value of Tests.
Abstract
Three types of in vitro released excretory, secretory and metabolic antigens of Wuchereria bancrofti third larval stage (L3ESM) are evaluated in ELISA test to detect infected individuals in the endemic area. A total of 104 reference sera are used to predict the sensitivity of these antigens. None of L3 ESM antigens, although homologous in nature, did not identify correctly the categorised reference sera. This study clearly indicated a need for defined antigens to detect W. bancrofti infection early in the endemic residents.
PubMed: 2187228
Affiliations:
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Desphande</name></author><author><name sortKey="Parab, P B" sort="Parab, P B" uniqKey="Parab P" first="P B" last="Parab">P B Parab</name></author><author><name sortKey="Rao, U R" sort="Rao, U R" uniqKey="Rao U" first="U R" last="Rao">U R Rao</name></author><author><name sortKey="Subrahmanyam, D" sort="Subrahmanyam, D" uniqKey="Subrahmanyam D" first="D" last="Subrahmanyam">D. Subrahmanyam</name></author></analytic><series><title level="j">Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ)</title><idno type="ISSN">0177-2392</idno><imprint><date when="1990" type="published">1990</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Helminth (analysis)</term><term>Antigens, Helminth (immunology)</term><term>Elephantiasis, Filarial (diagnosis)</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Filariasis (diagnosis)</term><term>Humans</term><term>Immune Sera (immunology)</term><term>Predictive Value of Tests</term><term>Wuchereria (immunology)</term><term>Wuchereria bancrofti (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antihelminthe (analyse)</term><term>Antigènes d'helminthe (immunologie)</term><term>Filariose lymphatique (diagnostic)</term><term>Filarioses (diagnostic)</term><term>Humains</term><term>Sérums immuns (immunologie)</term><term>Test ELISA</term><term>Valeur prédictive des tests</term><term>Wuchereria (immunologie)</term><term>Wuchereria bancrofti (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antibodies, Helminth</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Helminth</term><term>Immune Sera</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Anticorps antihelminthe</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Filariasis</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Filariose lymphatique</term><term>Filarioses</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes d'helminthe</term><term>Sérums immuns</term><term>Wuchereria</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Wuchereria</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Humans</term><term>Predictive Value of Tests</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Test ELISA</term><term>Valeur prédictive des tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Three types of in vitro released excretory, secretory and metabolic antigens of Wuchereria bancrofti third larval stage (L3ESM) are evaluated in ELISA test to detect infected individuals in the endemic area. A total of 104 reference sera are used to predict the sensitivity of these antigens. None of L3 ESM antigens, although homologous in nature, did not identify correctly the categorised reference sera. This study clearly indicated a need for defined antigens to detect W. bancrofti infection early in the endemic residents.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Desphande, L" sort="Desphande, L" uniqKey="Desphande L" first="L" last="Desphande">L. Desphande</name><name sortKey="Parab, P B" sort="Parab, P B" uniqKey="Parab P" first="P B" last="Parab">P B Parab</name><name sortKey="Rajasekariah, G R" sort="Rajasekariah, G R" uniqKey="Rajasekariah G" first="G R" last="Rajasekariah">G R Rajasekariah</name><name sortKey="Rao, U R" sort="Rao, U R" uniqKey="Rao U" first="U R" last="Rao">U R Rao</name><name sortKey="Subrahmanyam, D" sort="Subrahmanyam, D" uniqKey="Subrahmanyam D" first="D" last="Subrahmanyam">D. Subrahmanyam</name></noCountry><country name="Inde"><noRegion><name sortKey="Carvalho, P A" sort="Carvalho, P A" uniqKey="Carvalho P" first="P A" last="Carvalho">P A Carvalho</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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